OPIATES, RECEPTORS AND ENDORPHINS
نویسندگان
چکیده
منابع مشابه
Enkephalins and endorphins: the endogenous opiates.
The discovery of the opiate receptors in the central nervous system of man and subsequent identification of endogenous opiate-like ligands (enkephalins and endorphins) has provided a model for the analgesia, euphoria and addiction produced by the narcotics. In this article, the author reviews the background, biosynthesis and degradation, distribution, nociceptive transmission and analgesic effe...
متن کاملA brief history of opiates, opioid peptides, and opioid receptors.
It is hard to decide when and where the opium poppy was first cultivated. It may have been grown for its seeds before people discovered how to prepare mekonion from the leaves and fruits of the plant or opium (from "opos," the Greek word for juice) from the liquid that appears on the unripe seed capsule when it is notched. The use of written records to decipher the early history of opium use an...
متن کاملEndorphins, dopamine, and schizophrenia.
The theory that alterations of dopaminergic synaptic transmission may play a role in the pathogenesis of schizophrenia is widely accepted. A more recent theory links the endorphin system to the etiology of schizophrenia. We propose that these two theories may be combined into a single model. Recent neurochemical and pharmacological findings have indicated close functional relationships between ...
متن کاملAcupuncture and endorphins.
Acupuncture and electroacupuncture (EA) as complementary and alternative medicine have been accepted worldwide mainly for the treatment of acute and chronic pain. Studies on the mechanisms of action have revealed that endogenous opioid peptides in the central nervous system play an essential role in mediating the analgesic effect of EA. Further studies have shown that different kinds of neurope...
متن کاملEndorphins and psychiatry.
The term 'endorphin' (a combination of endogenous-morphine) is used to designate the entire group of peptides found in the brain and pituitary that mimic the biological properties of opiates. 'Endogenous opioid peptides', 'endogenous opioids' 'opioid peptide' and 'endopioids' can be considered as synonymous. Since the identification of stereospecific opiate receptors2J and the pentapeptides met...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1977
ISSN: 0007-0912
DOI: 10.1093/bja/49.6.523